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Elevated serum zonulin levels, as well as bacterial dysbiosis and a leaky gut barrier, have been observed in patients with rheumatoid arthritis, while subclinical intestinal inflammation has been observed in patients with ankylosing spondylitis [74, 75]

EGR1 regulates angiogenic and osteoclastogenic factors in prostate cancer and promotes metastasis

Increased plasma zonulin in patients with sepsis

In horses, the intestinal damage found in natural obstructions is likely related to the severity and duration of ischemia and the subsequent reperfusion injury [66]

It is a partial sequence of the naturally occurring gastric juice protein BPC, which was discovered in 1990 and found to play a protective role in the gastrointestinal tract